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BioVolume+ | Lip Microinfusion
BioVolume+ | Lip Microinfusion

“Fuller, hydrated lips — my friends noticed right away”

Thousands of women are giving up on the idea of cosmetic lip surgery after trying microinfusion — just 10 minutes a week.

  • Fuller, Defined Lips
  • 90-Day Money-Back Guarantee
  • Formulated in Italy
  • Dermatologist Tested

First results in 1–2 weeks. Collagen rebuilding is a process — most women see their best results between months 2 and 6. Results may vary.

The Italian standard for fuller lips

Ships within 1–2 business days

FREE Shipping over $49

Less than 1% of customers claim our 90-Day Money-Back Guarantee.

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Will BioVolume+ work for me?
Before and after lips — 3 applications Before and after lips — 2 applications

BioVolume+ was created for exactly what you're looking for: fuller, more hydrated, more defined lips, without needles or filler. Thousands of women have already made lip microinfusion their 10-minute weekly ritual, and many notice the first changes within 1–2 weeks. Results keep building with every application, with the best results typically between months 2 and 6.

And you start with total peace of mind. Every order is covered by our 90-day money-back guarantee: three full months to see the difference for yourself. Fewer than 1% of customers ever need it.

How does it work?

Our Lip Microinfusion System uses the new MicroSI™ Technology: 196 monocrystalline silicon microneedles, designed specifically for lips, which deliver the serum straight into the lip tissue with three settings for how much serum flows. Unlike traditional dermarollers that scratch and drag, BioVolume+ applies precise vertical pressure — for minimal irritation and high effectiveness.

The treatment works through three complementary actions: Volumizing: the peptide complex and hyaluronic acid plump the lips for a natural effect from the very first application. Smoothing: helps reduce lip lines and improve definition of the lip contour. Nourishing: squalane and ceramide NP nourish deeply and help strengthen the lipid barrier for softer lips.

Preparation: open a serum vial. Activation: place the MicroSI™ Technology applicator directly on top of the open vial — the needles soak up the serum instantly, with nothing to unscrew or fill. Application: apply with vertical pressure to lips and lip lines, 2-3 times per area. After treatment: let the serum absorb. The plumping effect is immediate, the hydration lasting.

Ten minutes a week is all it takes for visibly fuller, more defined lips.

The new MicroSI™ Technology

We've upgraded BioVolume+ to the new MicroSI™ Technology, designed specifically for the lip area:

  • 196 monocrystalline silicon microneedles — 0.25 mm long, designed specifically for the lips.
  • Applied directly on the vial — no more unscrewing and filling: open the serum vial and set the device on top. The needles soak up the serum instantly and you're ready to apply.
  • Three serum settings — choose the release intensity based on the area and your comfort level.
  • Stamp method — controlled vertical pressure, zero dragging, zero scratching.
  • Reusable across all 4 vials in the kit — just dab with cotton and alcohol between applications.

The result: faster, more precise, more hygienic application — designed for the delicacy of lip tissue.

Who is it for?

BioVolume+ is perfect for you if:

  • You want fuller lips without resorting to filler
  • You have those annoying lines above your lips
  • You want a safe alternative to in-office cosmetic treatments
  • You want immediate but natural-looking results

Important warnings:

  • Do not use if you have an active cold sore or open wounds on your lips
  • If you're prone to recurrent cold sores, consult your doctor before use: microneedling can reactivate the virus in predisposed individuals
  • Wait for any lesions to heal completely before starting treatment
Is it safe and painless?

Yes. MicroSI™ Technology was designed to be gentle on the delicate lip area. Its 196 monocrystalline silicon microneedles, designed specifically for lips, are 0.25 mm long and only reach the surface layer, exactly where the serum needs to go. Most customers feel a light tingling, and any mild redness fades within minutes.

Why it's gentler than the alternatives:

→ Lip filler is injected deep into the tissue, often with numbing cream, swelling and bruising. MicroSI™ stays at 0.25 mm, with no injection.

→ Dermarollers drag their needles sideways through the skin, often 0.5 mm deep. MicroSI™ presses straight down and lifts away: no scratching.

→ Plumping glosses swell your lips by irritating them with cinnamon or capsaicin, which is why they sting. Our serum hydrates instead of inflaming.

Lip-specific, three serum levels to dial in the intensity, compliant with European standards and recommended by the pharmacists who tested it.

Where can I use it?

Lips and perioral lines - the only areas it was specifically designed for.

As early as the first application you'll feel the immediate plumping effect. For lasting results, repeat every week.

What's inside?

Every BioVolume+ Kit includes:
→ 1 reusable MicroSI™ Technology applicator with 196 monocrystalline silicon microneedles (0.25 mm), designed specifically for lips
→ 4 vials of specialized serum with hyaluronic acid, squalane, ceramide NP and a peptide complex
→ Detailed step-by-step guide

A complete kit for 4 weeks of treatment (1 application per week)

The device is reusable: simply sanitize it with alcohol between uses

Ingredients & certifications
Ingredients & certifications

Serum ingredients: Aqua, Glycerin, Butylene Glycol, Mannitol, Sodium Lactate, Panthenol, Squalane, Bisabolol, Ceramide NP, PEG-40 Hydrogenated Castor Oil, Polysorbate 20, Sodium Hyaluronate, Ergothioneine, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, 1,2-Hexanediol, Hydroxyacetophenone, Carbomer, Arginine, Disodium EDTA.

MicroSI™ Technology: 196 monocrystalline silicon microneedles (0.25 mm) designed specifically for lips, three serum settings, reusable.

All our products are plant-derived, designed in the EU and recommended by the pharmacists who tested them.

Satisfaction guarantee
Satisfaction guarantee

We're so confident in our system that we offer a 90-day guarantee. If you're not completely satisfied with the results, we'll refund you in full. Contact customer service or see our return policy to start the process.

Which payment methods do you accept?
Which payment methods do you accept?

We accept all major credit cards and the other payment options shown at checkout.

Shipping and returns

We ship across the United States. Shipping times are shown on the purchase page. A simple return policy: you have 90 days to try the product. If it doesn't win you over, we'll refund you in full. Contact customer service or see our return policy to start the process.

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The science behind it

Microinfusion acts; everything else stops short

MicroSI™ Technology's 196 monocrystalline silicon microneedles, designed specifically for lips, help the serum penetrate the lip tissue, carrying volumizing actives where ordinary products can't reach. The serum gets to the deeper layers of the lips for a plumping effect from within.

BUILT FOR LIPS

The device that protects the health of your lips

The skin on your lips is among the thinnest on your face. Most plumping tools were designed for something else. BioVolume+ starts from the lips.

Glosses & plumpers

They irritate the surface

Cinnamon and capsaicin plumpers swell your lips by inflaming them. They sting, the effect fades by lunch, and nothing crosses the lip barrier.

  • Sting on contact
  • Fade within hours
  • Never get past the surface
Dermarollers

They drag, they don't press

A roller pulls its needles sideways through the skin, and many go 0.5 mm deep. On lips that means micro-scratches, more redness, and a wheel that is hard to clean between uses.

  • Needles enter at an angle
  • Often 0.5 mm: too deep for lips
  • Hard to clean between uses
Lip filler

It goes deep, and it stays

Filler is injected deep into the lip. The result depends on the hand holding the syringe, needs a touch-up every few months, and can't be adjusted at home.

  • Injection, deep in the tissue
  • $300 to $600 per syringe, every few months
  • Results depend on the injector
BioVolume+

The MicroSI™ Technology: 0.25 mm, straight down

MicroSI™ Technology presses 196 monocrystalline silicon microneedles, designed specifically for lips, 0.25 mm straight down into the lip surface, opens micro-channels, releases the serum and lifts away. No dragging, no injection. The channels close on their own and mild redness fades in 10–30 minutes.

  • 0.25 mm: the surface layer only
  • Vertical stamp, no sideways drag
  • Three serum settings to match your comfort
  • Reusable head, wipe-clean with alcohol
  • Serum in sealed single-dose vials
  • Suitable for most skin types

Skip treatments during an active cold sore and wait until it has fully healed. Once a week is all it takes: more often doesn't help.

EXPERT APPROVED

Recommended by pharmacists across Italy

COMPARISON

Why choose it?

What sets it apart from the alternatives.

The right choice

BioVolume+

Made for lips only
196 silicon microneedles, 0.25 mm
From $11 per session
10 minutes a week
Measured vertical pressure

In-clinic treatments

Effective, but expensive
Varies
$150–$350 per session
In-clinic only
Filler injections

Other products

Generally not effective
Varies
Varies
Inconsistent results
Brush or manual roller

BioVolume+ · 1 / 3

MEET WHO IS BEHIND IT

Formulated by Carolina Campana, PhD.

Scientific Director, Bioceutica Milano

Molecular biologist, 7 years in skincare. She's the one who decides what goes into our formulas. And, just as important, what doesn't.

FORMULATION

Ingredients that work.

Full transparency on our formula. Every ingredient has a specific role.

  • Peptide Complex
    Five peptides that speak to your cells: make more collagen. Acetyl Hexapeptide-8 softens lip lines. Palmitoyl Tripeptide-1 and Tetrapeptide-7 drive collagen synthesis. Tetrapeptide-9 and -11 support lip tissue regeneration. The result: lips that plump over time, not just after the first treatment.
  • Hyaluronic Acid
    It holds up to 1,000 times its weight in water. With microinfusion it reaches the deeper layers of the lip tissue — it doesn't stop at the surface the way a cream does. Lasting hydration, a physiological plumping effect from the very first application.
  • Squalane
    The emollient your lips already make on their own — just less of it over time. Squalane rebuilds the lipid barrier, stops dehydration and leaves lips soft without weighing them down.
  • Ceramide NP
    Ceramides are the mortar between skin cells. Without them the barrier crumbles and water evaporates. Ceramide NP keeps the lip barrier intact: less chapping, more softness, day after day.
EXPLORE THE FULL LIST
Ingredients: Water, Glycerin, Soluble Collagen, Butylene Glycol, Euglena Gracilis Polysaccharide, Xylitylglucoside, Anhydroxylitol, 1,2-Hexanediol, Betaine, Hydroxyacetophenone, Xylitol, Carbomer, Sodium Hyaluronate, Hydrolyzed Collagen, PEG-40 Hydrogenated Castor Oil, Hydrogenated Lecithin, Acetyl Hexapeptide-8, Sodium Lactate, Vanillyl Butyl Ether, Xanthan Gum, Sodium Hydroxide, Polysorbate 20, Ethylhexylglycerin, Ceramide NP, Ceramide AP, Ceramide NS, Ceramide EOP, Phytosphingosine, Cholesterol, Helichrysum Italicum Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7.

HOW TO USE

How to use BioVolume+

Ten minutes, once a week.

  1. Open the device and fill it with serum

    Open a serum vial and set the MicroSI™ Technology applicator on top: the needles soak up the serum instantly.

  2. Leave the device upside down for 2 minutes

    Turn it upside down for 2 minutes: the needles soak up the volumizing serum.

  3. Pat onto lips and target areas

    Focus on the lips and the areas you want to plump. Pat in circular motions for 2-3 passes.

  4. Massage in and let it absorb

    Massage in any remaining serum. The volumizing effect is visible after the very first application.

Community favorites

Rated 4.4 out of 5 · 339 reviews on Trustpilot

Genuinely excellent product!

Genuinely excellent product!! It has clearly improved the texture of my face. It's also incredibly easy to use — the treatment only takes 10 minutes. After buying the 9-month treatment I reordered right away. Really happy.

LiaSep 2026

I'm 52 and I've used Bioceutica for a year

I'm 52 and I've been using Bioceutica Milano products for a year. My experience has been exceptional: with the face and lip microinfusion treatments I got my glow back after early menopause left my skin dry and dull and my lips deflated. A professional approach you can do comfortably at home — that's the difference from the usual creams I used before. I saw significant, visible improvements from the very first treatments. Absolutely recommended.

GiusySep 2026

Third order for me

Third order for me, and this time along with BioVolume+ | Lip Microinfusion I also got BioInfusion+ | Microinfusion System and Infusion Patches. I received two free gifts as well. I hope everything is as exceptional as BioVolume for lips.

Lorena L.Sep 2026

I was skeptical, but I trusted it

I was skeptical, but I trusted it and I'm thrilled, because I had results from the second infusion. It does what it says. I'm stopping here — I'm not buying anything else, because I've finally found what I was looking for. No more money wasted. I got here and here I'm staying. Thank you!

VerdianaAug 2026

"You look so well!"

I'm 62 and since I started using Bioceutica microinfusion (about 3 months ago) everyone tells me how well I look. My nasolabial lines really are reduced, the lines above my lips are smoother, and overall my skin is more radiant and hydrated.

AnnaAug 2026

Maybe I'm a bit old to have started

Maybe I'm a bit old to have started the treatment in March 2026 at 61, but doing the microinfusion exactly every 10 days makes me feel like I'm pampering myself and taking care of the skin on my face and neck. I can't say I look 30 now, but just the act of 'pricking' myself with the serum makes me feel better when I look in the mirror.

PatriziaAug 2026

It won me over and it delivered

I'd used the product before and it had won me over. I reordered 2 face kits and 1 lip kit. Great product. Skin is brighter and firmer. Perfect for rehydrating after the summer. Fast delivery and responsive customer service.

LorenaAug 2026

Taking care of our skin

I used this product for about three months and I'm delighted with it. The results were visible even to people who don't see me every day and didn't know I was doing the treatment. I've bought the kit again and I'll be using it for the next 2–3 months.

DonatellaApr 2026

This is my second order

This is my second order and I can say I've seen some small improvements. The lip microinfusion is good, and so is the one for the face. My skin looks firmer and my lips fuller — but it takes consistency, a lot of consistency, and the commitment to keep the routine going.

MonicaAug 2026

Quality and professionalism

Customer support is prompt and thorough, and the products work if you use them consistently.

ClaudioJul 2026

Professional staff and great products

Professional staff and great products!

FrancescaAug 2026

Very good product

Very good product, it really helps with wrinkles — features look more defined. Of course it takes some time, but consistency and determination PAY OFF. I'm satisfied. Thank you!

JoleAug 2026

REAL CUSTOMER REVIEWS

What our customers say.

Read verified stories, photos and ratings from people who have already tried BioVolume+ | Lip Microinfusion.

FAQ

Your questions

What do I get, and how do I use it?

Every KIT includes 1 reusable MicroSI™ Technology applicator (196 monocrystalline silicon microneedles designed for lips, 3 serum settings) + 4 vials of specialized lip serum. Application couldn't be simpler: open a vial, place the MicroSI™ Technology applicator directly on top — the needles soak up the serum — then apply with gentle pressure to lips and lip lines. A detailed guide is included!

Is the device reusable?

Yes! The MicroSI™ Technology applicator is reusable across all 4 vials in the kit. Between applications just dab it with a little cotton and alcohol. Simple and hygienic.

How does lip microinfusion work?

The new MicroSI™ Technology's 196 monocrystalline silicon microneedles, designed specifically for lips, create micro-channels in the lip tissue, letting the serum penetrate deeply and plump from within. It's like bringing the effectiveness of an in-office cosmetic treatment straight to your home — with three serum settings so you can match it to your comfort.

How quickly will I see results?

You can see the plumping effect from the very first application: the micro-channels opened by MicroSI™ Technology let hyaluronic acid bind water in the surface layers of the lip tissue, for natural, physiological volume. For more noticeable results on tone and contour definition, many customers notice improvements after 2-3 regular applications. Individual results may vary.

Does it hurt?

Generally well tolerated. MicroSI™ Technology's 196 monocrystalline silicon microneedles are designed specifically for lips and calibrated to 0.25 mm for the delicate lip area. Most customers feel only a light tingling and the immediate plumping effect. Mild, temporary redness is normal and fades within minutes.

Does it work for men too?

Absolutely! Plenty of men use BioVolume+ for more defined lips and to soften lip lines. The results look completely natural.

Does it work on deep lip lines too?

Yes! The specialized peptides are particularly effective on deep perioral lines. You'll see progressive improvement week after week.

Is it safe on all skin types?

Yes, it's suitable for most skin types.

Important warnings:

  • Avoid use if you have an active cold sore or open wounds on your lips
  • If you get recurrent cold sores, consult your doctor before use
  • Microneedling can reactivate the herpes virus in predisposed individuals
  • If in doubt, consult your doctor or dermatologist
Is there any downtime?

Minimal downtime. Mild, temporary redness is normal and usually fades within 10-30 minutes. You can apply makeup or other lip products about 30 minutes after application, once the serum has fully absorbed.

Can I use other products afterward?

Of course! Wait for the serum to absorb (about 30 minutes), then you can apply lipstick, gloss or balm as usual. Though we think you won't need it 🥰

Can I use it if I've had lip filler or Botox?

Yes. Our product is generally compatible with filler or Botox. That said, we recommend checking with your injector or dermatologist if the procedure was recent.

Is there a satisfaction guarantee?

We offer a 90-day money-back guarantee. If you're not happy with the product, we'll refund you in full. Contact customer service or see our return policy to start the process.

Does the product renew automatically?

Only if you choose it. You can buy BioVolume+ as a one-time purchase, or choose Subscribe and save to get it delivered automatically every 1, 3 or 6 months at a lower price.

Need to pause or cancel your subscription? Just email us at support@bioceuticamilano.com and we'll take care of it.

Is it easy to use? Are the instructions any good?

Very easy! 4 simple steps in 10 minutes. You'll find a detailed illustrated guide in the box, plus video tutorials on our site.

Who should use BioVolume+?

Perfect for you if you want fuller lips without filler, want to reduce lip lines, or are looking for a safe alternative to in-office cosmetic treatments. Suitable for ages 25 and up.

What are the main ingredients?

Hyaluronic Acid, Squalane, Ceramide NP and a complex of 5 peptides (Acetyl Hexapeptide-8, Tetrapeptide-11, Tetrapeptide-9, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7). Together they deliver deep hydration, support the lipid barrier and support the skin's natural collagen production. European formula, paraben-free.

Can I use it with my own lip serums?

No, use only the included serum, which is specifically formulated for lip microneedling. Other products could cause irritation.

Is one vial enough? How much serum does it hold?

Yes, one vial covers lips and lip lines perfectly, with serum to spare. You can spread what's left on your lips as an extra treatment!

Can I use it on the rest of my face?

No, BioVolume+ is for lips only. For the face we have BioInfusion+, the complete anti-aging microinfusion system.

How often should I use it?

Once a week for optimal results. More often doesn't help, less often reduces effectiveness. Consistency is key!

Can I use it if I get cold sores?

If you have an active cold sore, wait until it has healed completely before use.

If you get recurring cold sores, we recommend consulting your doctor before starting treatment. By creating micro-channels in the skin, microneedling can potentially reactivate the herpes simplex virus in predisposed individuals.

Some customers with a history of recurrent cold sores take antiviral prophylaxis before treatment on their doctor's advice. If you have any doubts, talk to your own doctor.

What if I can't receive my subscription because I'm on vacation or away?

No problem. Write to our support (support@bioceuticamilano.com) and we'll pause the subscription together, for as long as you want.

When you come back, it picks up right where you left off. No cost, no commitment.