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BioInfusion+ | Microinfusion System

“Brighter, firmer skin from the very first application”

Thousands of women are putting off injectables after trying microinfusion at home — just 10 minutes a week.

  • Smoother, Firmer Skin
  • 90-Day Money-Back Guarantee
  • Formulated in Italy
  • Dermatologist Tested

First results in 1–2 weeks. Skin renewal is a process — most women see their best results between months 2 and 6. Results may vary.

Ships within 1–2 business days

FREE Shipping over $49

Less than 1% of customers claim our 90-Day Money-Back Guarantee.

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Will BioInfusion+ work for me?
BioInfusion+ | Microinfusion System BioInfusion+ | Microinfusion System

BioInfusion+ was created for exactly what you're looking for: smoother, firmer, more radiant skin, without injectables. Thousands of women dealing with wrinkles, fine lines and loss of firmness have already made microinfusion their 10-minute weekly ritual, and many notice the first changes within 1–2 weeks. Results keep building with every application, with the best results typically between months 2 and 6.

And you start with total peace of mind. Every order is covered by our 90-day money-back guarantee: three full months to see the difference for yourself. Fewer than 1% of customers ever need it.

How does it work?

Our Microinfusion System uses ultra-fine, painless micro-needles that create micro-channels in the skin's surface layer. This lets the collagen-peptide-rich serum penetrate deeply, where ordinary skincare can't reach. The treatment stimulates natural collagen production and helps even out the complexion and soften dark spots. A few minutes every 10-15 days is all it takes for more even, radiant skin.

Preparation:

  1. Open the device, fill it with serum and screw the needle head back on.
  2. Activation: turn it upside down for 1-2 minutes to let the serum flow.
  3. Application: gently pat over the skin (face, neck, areas with imperfections), repeating 2-3 times for optimal results.
  4. After treatment: apply the excess serum and let it absorb overnight. Avoid direct sun exposure for 12 hours.

On first use the device is sterile and ready to go. Before each later reuse, disinfect the head with rubbing alcohol on a cotton pad. Any leftover serum can be spread over face, neck and décolleté. A step-by-step guide is included in the box.

Who is it for?

The microinfusion system is the ideal choice if you're looking for an effective at-home treatment.

Recommended for all skin types and for anyone seeking a natural alternative to in-clinic treatments.

One caution, though: if you have active acne or rosacea, we strongly advise against using the product and recommend seeing a doctor.

Is it safe and painless?

Thanks to the ultra-fine 0.25 mm micro-needles, as thin as a hair, application is practically imperceptible and painless. Most customers describe only a light tingling.

Our Microinfusion System is: → Easy to use → Plant-derived → Made to EU standards (GMP ISO) → Designed in Europe together with our partners → Recommended by the pharmacists who tested it

Bioceutica Milano is an EUIPO registered trademark. Every product is created to strict quality and safety standards.

Where can I use it
Where can I use it

You can use it on any area of the face and neck affected by wrinkles and loss of elasticity.

From the very first treatment you'll notice firmer, more elastic, more radiant skin.

For results that last, we recommend repeating the treatment every 10 days.

What's inside?

Every Microinfusion Kit is designed for a specific number of treatments.

The micro-needle heads are sterile and should be used a maximum of three times to ensure hygiene and optimal results.

Kits available:
→ SINGLE KIT (1 month): 1 device and 3 serum vials (3 treatments)
→ DOUBLE KIT (2 months): 2 devices and 6 serum vials (6 treatments)
→ TRIPLE KIT (3 months): 3 devices and 9 serum vials (9 treatments)


PS: You also get a detailed guide for a perfect application.

Ingredients & certifications
Ingredients & certifications

All our products are plant-derived, designed in the EU, formulated to European standards (GMP ISO) and recommended by the pharmacists who tested them.

Ingredients: Water, Glycerin, Butanediol, 1,2-Hexanediol, Hydroxyacetophenone, Mannitol, Carbomer, Ergothioneine, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Citrus Aurantium Amara (Bitter Orange) Flower Oil, Sodium Hyaluronate, Arginine, Sodium Lactate, PEG-40 Hydrogenated Castor Oil, Polysorbate 20, 3-O-Ethyl Ascorbic Acid.

Satisfaction guarantee
Satisfaction guarantee

We're so confident in our system that we offer a 90-day guarantee. If you're not completely satisfied with the results, we'll refund you in full. Contact customer service or see our return policy to start the process.

Which payment methods do you accept?
Which payment methods do you accept?

We accept all major credit cards and the other payment options shown at checkout.

Shipping and returns

We ship across the United States. Shipping times are shown on the purchase page. A simple return policy: you have 90 days to try the product. If it doesn't win you over, we'll refund you in full. Contact customer service or see our return policy to start the process.

As seen in

The science behind it

Microinfusion goes where your skincare can't

Unlike traditional serums, the needle depth is enough to create micro-channels that increase absorption of the serum's active ingredients.

REAL RESULTS

These women saw a visible difference in under 90 days

Before and after — Bioceutica customer
Before and after — Bioceutica customer
Before and after — Bioceutica customer
Before and after — Bioceutica customer
Before and after — Bioceutica customer
Before and after — Bioceutica customer

EXPERT APPROVED

Recommended by pharmacists across Italy

COMPARISON

Why choose it?

What sets it apart from the alternatives.

The right choice

BioInfusion+

At home, whenever you want
From $10 per session
0.25 mm
Microinfusion with serum
Simple
Automatic and dosed

In-clinic treatments

By appointment
$150–$350 per session
Up to 2 mm
Various technologies
Requires a professional
Applied separately

Dermaroller

At home
$3–$5 per use
0.25-0.5 mm
Roller
Takes practice
Applied separately

BioInfusion+ · 1 / 3 — swipe to see other options

MEET WHO IS BEHIND IT

Formulated by Carolina Campana, PhD.

Scientific Director, Bioceutica Milano

Molecular biologist, 7 years in skincare. She's the one who decides what goes into our formulas. And, just as important, what doesn't.

FORMULATION

Ingredients that work.

Full transparency on our formula. Every ingredient has a specific role.

  • Collagen peptides
    Peptides plump the face and stimulate collagen production. The result is a visible reduction in wrinkles and fine lines.
  • Hyaluronic Acid
    Deep, lasting hydration. It supports cell regeneration and plumps the skin, softening wrinkles and expression lines.

  • Glycerin
    It strengthens the skin's natural barrier, smooths and softens skin, protects against dryness and irritation, and improves skin structure and refines its texture.
  • Vitamin C
    Vitamin C is a powerful antioxidant that helps keep skin young and radiant. It stimulates collagen production, reducing wrinkles and fine lines, and protects against sun and pollution damage, leaving skin smoother and more even. Used regularly, it gives the face a fresher, more radiant look.
EXPLORE THE FULL LIST
Ingredients: Water, Glycerin, Butanediol, 1,2-Hexanediol, Hydroxyacetophenone, Mannitol, Carbomer, Ergothioneine, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Citrus Aurantium Amara (Bitter Orange) Flower Oil, Sodium Hyaluronate, Arginine, Sodium Lactate, PEG-40 Hydrogenated Castor Oil, Polysorbate 20, 3-O-Ethyl Ascorbic Acid

HOW TO USE

How to use BioInfusion+

Ten minutes, every 10 days.

  1. Pour the serum into the device

    Unscrew the microneedle head and pour all the serum into the device.

  2. Wait 2 minutes

    Give the serum time to reach the microneedles, and cleanse your face while you wait.

  3. Pat onto the face

    Pass it gently over the whole face, going over areas again if needed.

  4. Spread any remaining serum

    Spread any leftover serum over your face with your hands, or use it on neck and décolleté.

Community favorites

Rated 4.4 out of 5 · 339 reviews on Trustpilot

Genuinely excellent product!

Genuinely excellent product!! It has clearly improved the texture of my face. It's also incredibly easy to use — the treatment only takes 10 minutes. After buying the 9-month treatment I reordered right away. Really happy.

LiaSep 2026

I'm 52 and I've used Bioceutica for a year

I'm 52 and I've been using Bioceutica Milano products for a year. My experience has been exceptional: with the face and lip microinfusion treatments I got my glow back after early menopause left my skin dry and dull and my lips deflated. A professional approach you can do comfortably at home — that's the difference from the usual creams I used before. I saw significant, visible improvements from the very first treatments. Absolutely recommended.

GiusySep 2026

Third order for me

Third order for me, and this time along with BioVolume+ | Lip Microinfusion I also got BioInfusion+ | Microinfusion System and Infusion Patches. I received two free gifts as well. I hope everything is as exceptional as BioVolume for lips.

Lorena L.Sep 2026

I was skeptical, but I trusted it

I was skeptical, but I trusted it and I'm thrilled, because I had results from the second infusion. It does what it says. I'm stopping here — I'm not buying anything else, because I've finally found what I was looking for. No more money wasted. I got here and here I'm staying. Thank you!

VerdianaAug 2026

"You look so well!"

I'm 62 and since I started using Bioceutica microinfusion (about 3 months ago) everyone tells me how well I look. My nasolabial lines really are reduced, the lines above my lips are smoother, and overall my skin is more radiant and hydrated.

AnnaAug 2026

Maybe I'm a bit old to have started

Maybe I'm a bit old to have started the treatment in March 2026 at 61, but doing the microinfusion exactly every 10 days makes me feel like I'm pampering myself and taking care of the skin on my face and neck. I can't say I look 30 now, but just the act of 'pricking' myself with the serum makes me feel better when I look in the mirror.

PatriziaAug 2026

It won me over and it delivered

I'd used the product before and it had won me over. I reordered 2 face kits and 1 lip kit. Great product. Skin is brighter and firmer. Perfect for rehydrating after the summer. Fast delivery and responsive customer service.

LorenaAug 2026

Taking care of our skin

I used this product for about three months and I'm delighted with it. The results were visible even to people who don't see me every day and didn't know I was doing the treatment. I've bought the kit again and I'll be using it for the next 2–3 months.

DonatellaApr 2026

This is my second order

This is my second order and I can say I've seen some small improvements. The lip microinfusion is good, and so is the one for the face. My skin looks firmer and my lips fuller — but it takes consistency, a lot of consistency, and the commitment to keep the routine going.

MonicaAug 2026

Quality and professionalism

Customer support is prompt and thorough, and the products work if you use them consistently.

ClaudioJul 2026

Professional staff and great products

Professional staff and great products!

FrancescaAug 2026

Very good product

Very good product, it really helps with wrinkles — features look more defined. Of course it takes some time, but consistency and determination PAY OFF. I'm satisfied. Thank you!

JoleAug 2026

REAL CUSTOMER REVIEWS

What our customers say.

Read verified stories, photos and ratings from people who have already tried BioInfusion+ | Microinfusion System.

FAQ

Your questions

Do I have to keep using it forever to maintain results?

No. The basic course is 3 sessions (1 month) for the first visible results, 9 sessions (3 months) for the full result. After that, 1-2 sessions a month are enough to maintain. If you stop, your skin doesn't get worse than before — you keep the improvements you've made.

I have sensitive skin or allergies. Can I use it?

BioInfusion+ is formulated without fragrance, parabens or alcohol — plant-derived and certified vegan. Active ingredients: Peptides, Vitamin C, Hyaluronic Acid. If you have specific allergies to these ingredients, check with your dermatologist before use. Either way, our 90-day guarantee always applies: if it isn't right for you, contact customer service or see our return policy and we'll refund you in full.

Can it be used on lips and around the eyes?

Yes. BioInfusion+ is safe for the lines above the lips and for the eye area — two of the areas our customers ask about most. Use light pressure on these delicate spots. Avoid direct contact with the eyelids and mucous membranes.

Does it work on the vertical lines above the lips?

Yes, it's one of the most popular uses. The vertical lines above the lips respond well to microinfusion because the peptides and hyaluronic acid are deposited directly into the dermis — where topical creams can't reach. Results show after just the first few sessions.

Which payment methods do you accept?

We accept all major credit cards and the other payment options shown at checkout.

How much product do I get, and how do I use it?

Every kit includes:
→ SINGLE KIT (1 month): 1 sterile device and 3 serum vials (3 treatments)
→ DOUBLE KIT (2 months): 2 sterile devices and 6 serum vials (6 treatments)
→ TRIPLE KIT (3 months): 3 sterile devices and 9 serum vials (9 treatments)


One treatment every 10 days is recommended.

You also get a detailed video guide.

Are the heads reusable?

Yes. Each head in the Microinfusion Kit can be used up to three times. Every pack contains three serums, so you can use the same head for the whole course of treatment. Disinfect the head with alcohol after every use and before every use. After the three sessions, dispose of the used head.

How does Bioceutica Microinfusion work?

Our Microinfusion System uses ultra-fine, painless micro-needles to create micro-channels in the skin's first layer.

This lets the serum, with hyaluronic acid and collagen peptides, reach the deeper layers where ordinary anti-aging products can't.

That stimulates collagen production — the real driver behind wrinkles and fine lines.

How quickly will I see results?

Right after the first session you'll notice smoother, plumper, more hydrated skin. Many customers see a visible reduction in fine lines from the very first application. Fuller results take consistency: over the complete cycle of 9 treatments spread across 2-3 months (one session every 10-15 days) skin looks progressively firmer and more even.

Does it hurt?

No. Thanks to the 0.25 mm micro-needles — as thin as a hair — application is practically imperceptible. Most people describe only a light tingling.

Does it work for men too?

Absolutely! The Microinfusion Kit works for every skin type, for men and women alike.

It acts on wrinkles, fine lines, dark spots and uneven texture regardless of gender.

Does it work on deep wrinkles too?

Yes, the Microinfusion Kit can improve the look of deep wrinkles by stimulating collagen production and hydrating the skin. Results on deep wrinkles take longer, typically 3-6 months of consistent use.

Is it safe for all skin types?

Yes! Our system is safe for all skin types, sensitive skin included. If you have a skin condition, check with your dermatologist first.

Is there any downtime?

Downtime is minimal. You may notice slight redness or sensitivity right after treatment, which fades within a few hours. Avoid sun and makeup for 12 hours — not an issue if you treat in the evening. Avoid harsh actives like retinol for 24 hours.

Can I use hyaluronic acid and retinol after this product?

You can apply your usual hyaluronic acid skincare the same evening as the treatment, which supports hydration and results. Avoid retinol or other strong actives like acids for 24-48 hours after treatment. Don't apply makeup, and keep skin clean for about 12 hours.

Can I use it if I'm having LED or RF treatments?

Yes, the kit can be combined with LED or RF. Wait at least two nights after using the kit before those treatments to get the most out of both.

Can I use the product if I've had filler or Botox?

Yes, you can use the kit after filler or Botox too. Wait at least two weeks after the injectable treatment to let the product settle.

Is there a 90-day satisfaction guarantee on every kit?

Yes, Bioceutica offers a 90-day guarantee on every Microinfusion Kit, including the 1- and 2-month ones. For a refund, contact our team at support@bioceuticamilano.com or see our return policy: we'll walk you through it step by step.

Does the product renew and ship automatically every month?

No, the Microinfusion Kit has no renewals or monthly subscriptions. Every purchase is one-time. To get another kit you'll need to place a new order.

Is it easy to use? Are the instructions any good?

Yes. The Microinfusion Kit is simple to use and takes only 10-15 minutes per session. Every order includes a video guide and a detailed manual covering every step, from prep to applying the serum.

Who should use the microinfusion kit?

Collagen production starts to decline from age 25. The kit is ideal for adults between 25 and 80 who want to improve the look of their skin.

It helps reduce wrinkles, fine lines, dark spots and uneven texture. It isn't recommended for anyone with rosacea, eczema or active acne.

For specific conditions, consult your dermatologist.

What are the ingredients?

Collagen peptides: they stimulate natural collagen production for firmer, more elastic skin. They visibly reduce wrinkles and fine lines, improve skin structure and refine skin texture.

Hyaluronic Acid: hydrates deeply, holding up to 1,000 times its weight in water. It plumps the skin, softening wrinkles and expression lines.

Glycerin: strengthens the skin's natural barrier. It smooths and softens skin and protects against dryness and irritation.

Ingredients: Water, Glycerin, Butanediol, 1,2-Hexanediol, Hydroxyacetophenone, Mannitol, Carbomer, Ergothioneine, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Citrus Aurantium Amara (Bitter Orange) Flower Oil, Sodium Hyaluronate, Arginine, Sodium Lactate, PEG-40 Hydrogenated Castor Oil, Polysorbate 20, 3-O-Ethyl Ascorbic Acid.

Can I use it with my own serums?

We advise against using serums other than the one provided. Ours is specifically formulated to work in synergy with the microinfusion technology.

Is one vial enough for face and neck?

Yes, there's enough serum to treat face and neck. You'll likely have some left over, which you can apply after treatment to maximize hydration and absorption.

Can I use it on my eyelids?

The micro-needle device isn't meant for use on the eyelids. But once you've finished the treatment you can spread any leftover serum on your eyelids too.

What if I can't receive my subscription because I'm on vacation or away?

No problem. Write to our support (support@bioceuticamilano.com) and we'll pause the subscription together, for as long as you want.

When you come back, it picks up right where you left off. No cost, no commitment.